深圳市前海香港商会于2015年12月7日成立，原香港特区行政长官林郑月娥，原香港中联办副主任仇鸿，原广东省委副书记、深圳市委书记马兴瑞，原深圳市委副书记、市长许勤以及招商局集团董事长李建红共同为前海香港商会揭牌，并对商会给予了大力的支持。
《2021年完善选举制度（综合修订）条例草案》通过后，前海香港商会作为内地港人团体代表，在香港选举委员会第四界别分组中获得席位，参与选举行政长官、立法会议员等职责，是深圳唯一一家获得选举投票权的商会，目前商会业务联络主管单位为香港中联办及前海管理局。
前海香港商会作为第一家由港资企业为主、深港企业结合组成的社会组织，义不容辞的集聚、动员并发挥民间社会资源和力量，将促进深港合作发展为使命，将香港资源引进内地、将内地资源输入香港，实现内地、粤港澳大湾区之问的经济资源、人力资源、文化资源、技术资源共通和分享。前海香港商会将不仅成为会员企业之间交流和合作的平台，也将致力于成为会员企业与粤港澳大湾区其他企业、政府部门、商业机构以及其他组织之间开展合作和沟通的桥梁。前海香港商会目前已汇集了包括佳宁娜集团、嘉里建设、华商林李黎（前海）联营律师事务所、金银业贸易场、招商局集团、华润集团、南海控股、中建国际、普华永道、毕马威、九龙仓、世茂集团、利丰集团、周大福集团、新世界发展有限公司、东亚银行、渣打银行、香江金融等知名企业，企业会员数量超过300家。
The Hong Kong Chamber of Commerce (Qianhai) was established in Shenzhen on December 7, 2015, which has received strong support from governments at all levels, including the authorities of HKSAR, Guangdong Province, Shenzhen City, and Qianhai Zone.
In 2021, as a representative of long-term Hong Kong residents in the Chinese mainland, HKCCQ successfully obtained a seat in the fourth sector of the Hong Kong Election Committee, which participates in the election of the Hong Kong Chief Executive and Legislative Council members. It is the only one non-governmental organization in Shenzhen that has the voting right in Hong Kong official elections.
HKCCQ is the first nonprofit-commercial organization mainly composed of Hong Kong-funded enterprises, with a mission to strengthen the relationship between Shenzhen and Hong Kong. Specifically, HKCCQ aims to improve two-way connections of business, human resources, culture, and technology between HKSAR and Chinese Mainland, creating a platform for members, local governments, and other organizations. Currently, HKCCQ has attracted over 300 corporate members, including well-known Hong Kong-funded companies, state-owned enterprises, and SMEs from various industries.